Behaviour Issues in Autism

Behaviour Issues in Autism

  • Stereotypical
  • Repetitive
  • Obsessive and Compulsive Behaviours
  • Aggression and irritability
  • Hyperactivity

Children and adults have behaviours that make it difficult to learn, interact socially or function in different aspects of life.

While the underlying contributors to these behaviours are poorly understood biomedical treatment has been shown to dramatically improve these “autistic” symptoms by:

  1. Improving methylation and increasing glutathione

    • The methylation cycle is responsible for supporting 200 other cycles in the body including producing and regulating brain chemicals and making glutathione.
    • Brain chemical balance is an important part of treating “autistic” behaviours with biomedical treatment. Improved serotonin, dopamine and GABA production help to not only optimize development but decrease behaviours across the board
    • Glutathione is not only an important antioxidant that helps to reduce oxidative stress and improve mitochondrial function; it is also the way that glutamate is managed in the brain. High levels of glutamate have been identified in autism and may explain many symptoms of ASD.
    • Methyl B12 injections, B6, magnesium and n-acetyl-cysteine have all been shown in clinical trials to reduce behaviours in autism; they all also support the production of glutathione.
  2. Improving microbiome / digestive health

    • Pain is the root of many behaviours seen in autism
    • Chronic constipation, diarrhea, reflux and other digestive disorders cause pain and discomfort. Up to 85% of people with autism have digestive dysfunction
    • Altered microbiota in the gut impact brain function and likely contribute directly to autistic behaviours. A recent study showed microbes were capable of “eating” GABA, a brain chemical needed to calm the brain, in contrast to glutamate which creates potentially toxic levels of excitement (see immunoexcitotocicity).
    • The Human Microbiome Project (HMP) research has shown the gut and brain are interconnected and that disruption in one will cause disruption in the other; the gut-brain axis. Altered microbiota and microbiome function is found in autism decreasing the guts ability to function.
    • Indirectly, the microbiome will cause behavioural concerns in autism by shifting food craving toward sugar, dairy and complex carbohydrates in an attempt to stem the cell danger response resulting in altered neurotransmission, sleep disruption, irritability, aggression and mood swings
    • The gut is responsible for making brain chemicals required to process sensory information. Impaired gut function results in abnormal neurotransmission contributing to sensory issues in autism
    • Sleep problems are extremely common in autism including difficulty with sleep onset, latency and maintenance
    • The methylation cycle makes melatonin, which is often deficient in autism
    • Sleep disturbances are a major contributor to behavioural issues in addition to decreasing optimal development of language, social and cognitive skills
  3. Improving mitochondrial function

    • Mitochondria produce all the energy in the body
    • Mitochondrial impairment is a hallmark of autism
    • Decreased energy production will contribute to behavioural issues in a number of different ways including temper tantrums, hyperactivity (in an effort to produce more energy to compensate), irritability, lethargy